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| Physical Characters and Index |
Name: H-glu-lys-pro-lys-val-glu-ala-tyr-lys-ala-ala-ala-pro-ala-OH
CAS number: 444305-16-2
Molecular formula: C70H114N18O21
Molecular weight: 1543.78 |
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| Use and description |
| MBP (85-99) peptide antagonist, or J5, is a 15 amino acid peptide fragment designed on the binding motif of MBP 85-99 (myelin basic protein 85-99) to HLA-DR2 (human leukocyte antigen-DR2), which competes with and inhibits the binding of MBP (85-99) to HLA-DR2 and IL-2. MBP 85-99 is the the immunodominant epitope of MBP and a major candidate autoantigen in multiple sclerosis (MS), making this peptide a useful tool for MS research. |
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